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June 18, 2024
This study, conducted by researchers from University College London (UCL) and University College London Hospitals (UCLH), offers important insights into the brain areas that enable us to solve problems without prior experience—known as fluid intelligence. Fluid intelligence is a vital aspect of human cognition, involving mental processes like abstraction, judgment, attention, and strategy generation. It plays a key role in daily tasks such as planning, organizing, and decision-making, and is closely linked to success in education, professional life, and overall well-being.
The researchers used a novel approach called “lesion-deficit mapping” to better understand the brain regions responsible for fluid intelligence. Previous studies often relied on functional imaging techniques like fMRI, which measure brain activity but can sometimes provide incomplete or misleading information about specific brain areas. In contrast, lesion-deficit mapping focuses on patients who have suffered damage to particular brain regions, allowing researchers to observe how these injuries affect cognitive abilities. This method provides a clearer link between brain structures and their functions.
The study involved 227 patients who had brain injuries caused by either tumors or strokes. To assess their fluid intelligence, the researchers used the Raven Advanced Progressive Matrices (APM), a well-established test. The APM consists of visual pattern problems where participants must choose the missing piece from a set of options. This test is designed to evaluate problem-solving skills, one of the core components of fluid intelligence.
By combining lesion-deficit mapping with data from the APM test, the researchers were able to pinpoint the specific brain areas involved in fluid intelligence. They discovered that patients with damage to the right frontal region of the brain showed the most significant impairments in their ability to solve problems. This finding suggests that the right frontal lobe plays a critical role in high-level cognitive processes like reasoning, abstraction, and strategic thinking. While earlier research suggested that a larger network of brain regions might be involved, this study narrows it down to the right frontal region.
These findings have practical implications for clinical settings, as the APM test can be used to help diagnose right frontal lobe dysfunction. It also highlights the value of focusing on lesion studies to better understand the relationship between brain structures and cognitive abilities. This could lead to improved treatment strategies for patients with neurological conditions such as traumatic brain injury, stroke, or dementia. Overall, this research provides important new evidence about the brain’s role in fluid intelligence, offering a more precise understanding of how we solve novel problems.
The study was led by Professor Lisa Cipolotti from UCL’s Queen Square Institute of Neurology.